Donepezil is more effective than galantamine for mild to moderate Alzheimer's disease.
نویسنده
چکیده
Jones RW, Soininen H, Hager K, et al. A multinational, randomised, 12-week study comparing the effects of donepezil and galantamine in patients with mild to moderate Alzheimer’s disease. Int J Geriatr Psychiatry 2004;19:58–67. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
منابع مشابه
Galantamine versus donepezil in Chinese patients with Alzheimer’s disease: results from a randomized, double-blind study
BACKGROUND Acetylcholinesterase inhibitors are considered standard of care for Alzheimer's disease in many countries. Galantamine is an acetylcholinesterase inhibitor that may also act via allosteric modulation of nicotinic acetylcholine receptors. Therefore, it may provide benefits compared with other acetylcholinesterase inhibitors. The present study compared galantamine (n = 116) with donepe...
متن کاملCurrent and Emerging Pharmacological Treatment Options for Dementia
Treatments for the symptomatic relief of Alzheimer's disease are available but despite advances in our ability to treat persons with various forms of dementia, more effective treatments are needed. The cholinesterase inhibitors donepezil, rivastigmine, and galantamine have demonstrated efficacy in improving cognition and global status and to a lesser extent, behavioral abnormalities relative to...
متن کاملPHA 3611/3612 Clinical Pharmacy Clerkship
Generic Name: Galantamine Brand Name: Reminyl® Manufacturer: Shire Pharmaceuticals and Janssen Cilag (http://www.janssenpharmaceutica.be/index_N.asp) Summary: Galantamine hydrobromide, a phenanthrene alkaloid, is a reversible, competitive acetylcholinesterase inhibitor that is structurally unrelated to other acetylcholinesterase inhibitors (e.g, donepezil, rivastigmine, tacrine). Galantamine hy...
متن کاملSafety and tolerability of donepezil, rivastigmine and galantamine for patients with Alzheimer's disease: systematic review of the 'real-world' evidence.
BACKGROUND/AIMS The purpose of this systematic review was to compare the safety and tolerability of the cholinesterase inhibitors (ChEIs) donepezil, rivastigmine and galantamine for treating mild to moderate Alzheimer's disease (AD) patients in routine clinical practice. METHODS Electronic databases (Cochrane Library, Medline, EMBASE; accessed October 2008) and manual bibliographic searches w...
متن کاملThe Effects of an Uninterrupted Switch from Donepezil to Galantamine without Dose Titration on Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease
AIMS To elucidate the efficacy of galantamine on cognition and behavioral and psychological symptoms of dementia (BPSD) in outpatients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) who have switched from donepezil to galantamine. MATERIALS AND METHODS We performed an uninterrupted switch from donepezil to galantamine without a washout period or dose titration in 44 ambulat...
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ورودعنوان ژورنال:
- Evidence-based mental health
دوره 7 3 شماره
صفحات -
تاریخ انتشار 2004